{
  "resourceType": "CodeSystem",
  "id": "certainty-subcomponent-type",
  "meta": {
    "lastUpdated": "2018-12-27T22:37:54.724+11:00"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "cds"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "trial-use"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 0
    }
  ],
  "url": "http://terminology.hl7.org/CodeSystem/certainty-subcomponent-type",
  "identifier": [
    {
      "system": "urn:ietf:rfc:3986",
      "value": "urn:oid:2.16.840.1.113883.4.642.1.1360"
    }
  ],
  "version": "4.0.0",
  "name": "CertaintySubcomponentType",
  "title": "CertaintySubcomponentType",
  "status": "draft",
  "experimental": false,
  "date": "2018-12-27T22:37:54+11:00",
  "publisher": "HL7 (FHIR Project)",
  "contact": [
    {
      "telecom": [
        {
          "system": "url",
          "value": "http://hl7.org/fhir"
        },
        {
          "system": "email",
          "value": "fhir@lists.hl7.org"
        }
      ]
    }
  ],
  "description": "The subcomponent classification of quality of evidence rating systems.",
  "caseSensitive": true,
  "valueSet": "http://hl7.org/fhir/ValueSet/certainty-subcomponent-type",
  "content": "complete",
  "concept": [
    {
      "code": "RiskOfBias",
      "display": "Risk of bias",
      "definition": "methodologic concerns reducing internal validity."
    },
    {
      "code": "Inconsistency",
      "display": "Inconsistency",
      "definition": "concerns that findings are not similar enough to support certainty."
    },
    {
      "code": "Indirectness",
      "display": "Indirectness",
      "definition": "concerns reducing external validity."
    },
    {
      "code": "Imprecision",
      "display": "Imprecision",
      "definition": "High quality evidence."
    },
    {
      "code": "PublicationBias",
      "display": "Publication bias",
      "definition": "likelihood that what is published misrepresents what is available to publish."
    },
    {
      "code": "DoseResponseGradient",
      "display": "Dose response gradient",
      "definition": "higher certainty due to dose response relationship."
    },
    {
      "code": "PlausibleConfounding",
      "display": "Plausible confounding",
      "definition": "higher certainty due to risk of bias in opposite direction."
    },
    {
      "code": "LargeEffect",
      "display": "Large effect",
      "definition": "higher certainty due to large effect size."
    }
  ]
}