blastx BLASTX 2.2.28+ Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. ../../../ncbi-blast-2.2.28+/db/nr/nr Query_1 sequence that generates AAP36446 protein 219 BLOSUM62 10 11 1 L; 1 Query_1 sequence that generates AAP36446 protein 219 1 gi|30584395|gb|AAP36446.1| Homo sapiens insulin [synthetic construct] >gi|60653573|gb|AAX29480.1| insulin [synthetic construct] >gi|60653575|gb|AAX29481.1| insulin [synthetic construct] AAP36446 111 1 149.443 376 1.85749e-44 1 219 39 111 1 0 73 73 0 73 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCNL LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCNL LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCNL 2 gi|4557671|ref|NP_000198.1| insulin preproprotein [Homo sapiens] >gi|297374821|ref|NP_001172026.1| insulin preproprotein [Homo sapiens] >gi|297374823|ref|NP_001172027.1| insulin preproprotein [Homo sapiens] >gi|426366889|ref|XP_004050475.1| PREDICTED: insulin isoform 1 [Gorilla gorilla gorilla] >gi|426366891|ref|XP_004050476.1| PREDICTED: insulin isoform 2 [Gorilla gorilla gorilla] >gi|124617|sp|P01308.1|INS_HUMAN RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor >gi|52000618|sp|Q6YK33.1|INS_GORGO RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor >gi|386828|gb|AAA59172.1| insulin [Homo sapiens] >gi|386829|gb|AAA59173.1| insulin [Homo sapiens] >gi|394766|emb|CAA49913.1| pre-proinsulin [Homo sapiens] >gi|758088|emb|CAA23828.1| preproinsulin [Homo sapiens] >gi|13528924|gb|AAH05255.1| Insulin [Homo sapiens] >gi|22901140|gb|AAN06935.1| insulin precursor [Gorilla gorilla] >gi|23986711|gb|AAN39451.1| insulin [Homo sapiens] >gi|30582455|gb|AAP35454.1| insulin [Homo sapiens] >gi|59036749|gb|AAW83741.1| proinsulin [Homo sapiens] >gi|61361296|gb|AAX42025.1| insulin [synthetic construct] >gi|61361299|gb|AAX42026.1| insulin [synthetic construct] >gi|119622893|gb|EAX02488.1| insulin, isoform CRA_a [Homo sapiens] >gi|119622894|gb|EAX02489.1| insulin, isoform CRA_a [Homo sapiens] >gi|123992113|gb|ABM83966.1| insulin [synthetic construct] >gi|123999448|gb|ABM87282.1| insulin [synthetic construct] >gi|306921727|dbj|BAJ17943.1| insulin [synthetic construct] >gi|389620191|gb|AFK93533.1| preproinsulin [Homo sapiens] >gi|223160|prf||0601246A insulin,prepro NP_000198 110 1 147.902 372 6.2941e-44 1 216 39 110 1 0 72 72 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 3 gi|48428254|sp|Q8HXV2.1|INS_PONPY RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor >gi|22901146|gb|AAN06937.1| insulin precursor [Pongo pygmaeus] Q8HXV2 110 1 147.902 372 7.32809e-44 1 216 39 110 1 0 72 72 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 4 gi|57113877|ref|NP_001008996.1| insulin preproprotein [Pan troglodytes] >gi|266377|sp|P30410.1|INS_PANTR RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor >gi|38252|emb|CAA43403.1| Preproinsulin [Pan troglodytes] >gi|22901134|gb|AAN06933.1| insulin precursor [Pan troglodytes] NP_001008996 110 1 147.902 372 7.65358e-44 1 216 39 110 1 0 72 72 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 5 gi|208668|gb|AAA72172.1| synthetic preproinsulin [synthetic construct] AAA72172 114 1 147.517 371 1.05685e-43 1 216 43 114 1 0 72 72 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 6 gi|58103|emb|CAA23424.1| unnamed protein product [synthetic construct] >gi|208670|gb|AAA72531.1| proinsulin [synthetic construct] >gi|237679346|dbj|BAH59081.1| human M-proinsulin [synthetic construct] CAA23424 87 1 146.747 369 1.13542e-43 1 216 16 87 1 0 72 72 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 7 gi|333826819|gb|AEG19452.1| insulin [Homo sapiens] AEG19452 94 1 146.362 368 1.47801e-43 1 216 23 94 1 0 72 72 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 8 gi|452814811|gb|AGG11869.1| HPPI [synthetic construct] AGG11869 97 1 145.591 366 3.19394e-43 1 216 26 97 1 0 71 71 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQVEQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDLQV QVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 9 gi|402892446|ref|XP_003909425.1| PREDICTED: insulin isoform 1 [Papio anubis] >gi|402892448|ref|XP_003909426.1| PREDICTED: insulin isoform 2 [Papio anubis] >gi|402892450|ref|XP_003909427.1| PREDICTED: insulin isoform 3 [Papio anubis] >gi|402892452|ref|XP_003909428.1| PREDICTED: insulin isoform 4 [Papio anubis] XP_003909425 110 1 145.206 365 8.26074e-43 1 216 39 110 1 0 71 71 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 10 gi|332264753|ref|XP_003281396.1| PREDICTED: insulin isoform 1 [Nomascus leucogenys] >gi|332264759|ref|XP_003281399.1| PREDICTED: insulin isoform 4 [Nomascus leucogenys] >gi|441609417|ref|XP_004087913.1| PREDICTED: insulin [Nomascus leucogenys] >gi|441609429|ref|XP_004087914.1| PREDICTED: insulin [Nomascus leucogenys] >gi|266373|sp|P30406.1|INS_MACFA RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor >gi|342122|gb|AAA36849.1| preproinsulin [Macaca fascicularis] XP_003281396 110 1 145.206 365 8.44215e-43 1 216 39 110 1 0 71 71 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 11 gi|266362|sp|P30407.1|INS_CERAE RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor >gi|22809|emb|CAA43405.1| Preproinsulin [Chlorocebus aethiops] P30407 110 1 145.206 365 8.81699e-43 1 216 39 110 1 0 71 71 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 12 gi|223965|prf||1006230A insulin,pro- 1006230A 86 1 143.665 361 1.5846e-42 1 216 15 86 1 0 71 71 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAEDPQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAED QVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 13 gi|284793774|pdb|2KQP|A Chain A, Nmr Structure Of Proinsulin 2KQP_A 86 1 140.969 354 1.90992e-41 1 216 15 86 1 0 70 70 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTKPTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYT TRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 14 gi|395742280|ref|XP_003777725.1| PREDICTED: LOW QUALITY PROTEIN: insulin [Pongo abelii] XP_003777725 111 1 140.198 352 7.45132e-41 1 216 40 111 1 0 69 70 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLLFGERGFFYTPKTRREAEDLAVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYL+ GERGFFYTPKTRREAEDL VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 15 gi|444731569|gb|ELW71922.1| Insulin [Tupaia chinensis] ELW71922 110 1 135.961 341 3.19511e-39 1 216 39 110 1 0 67 67 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREVEDSQVGQVELGGGPGAGSLQPLALEVPPQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRRE ED QVGQVELGGGPGAGSLQPLALE QKRGIVEQCCTSICSLYQLENYCN 16 gi|307072|gb|AAA59179.1| insulin [Homo sapiens] AAA59179 107 1 135.961 341 3.45255e-39 1 216 39 107 1 0 69 69 3 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAE---VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKTRREAE VGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN 17 gi|194272230|ref|NP_001123565.1| insulin precursor [Canis lupus familiaris] >gi|124575|sp|P01321.1|INS_CANFA RecName: Full=Insulin; Contains: RecName: Full=Insulin B chain; Contains: RecName: Full=Insulin A chain; Flags: Precursor >gi|995|emb|CAA23475.1| preproinsulin [Canis sp.] NP_001123565 110 1 131.724 330 1.51762e-37 1 216 39 110 1 0 63 64 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKARREVEDLQVRDVELAGAPGEGGLQPLALEGALQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPK RRE EDLQV VEL G PG G LQPLALEG+LQKRGIVEQCCTSICSLYQLENYCN 18 gi|217418318|gb|ACK44319.1| insulin (predicted) [Oryctolagus cuniculus] ACK44319 110 1 129.413 324 1.11514e-36 1 216 39 110 1 0 63 66 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKSRREVEELQVGQAELGGGPDAGGLQPSALELALQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPK+RRE E+LQVGQ ELGGGP AG LQP ALE +LQKRGIVEQCCTSICSLYQLENYCN 19 gi|472368670|ref|XP_004403859.1| PREDICTED: insulin isoform 2 [Odobenus rosmarus divergens] XP_004403859 110 1 129.028 323 1.59455e-36 1 216 39 110 1 0 62 63 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPKARREVEDPQARDVELGGAPGMGGLQPLALEGALQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPK RRE ED Q VELGG PG G LQPLALEG+LQKRGIVEQCCTSICSLYQLENYCN 20 gi|82749730|gb|ABB89749.1| preproinsulin 2 [Mus caroli] ABB89749 110 1 125.946 315 2.7249e-35 1 216 39 110 1 0 60 64 0 72 LYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN LYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAGDLQTLALEVAQQKRGIVDQCCTSICSLYQLENYCN LYLVCGERGFFYTP +RRE ED QV Q+ELGGGPGAG LQ LALE + QKRGIV+QCCTSICSLYQLENYCN 32052081 11116435548 44 281478175536 0.041 0.267 0.14