{
  "resourceType": "CodeSystem",
  "id": "referencerange-meaning",
  "meta": {
    "lastUpdated": "2018-12-27T22:37:54.724+11:00",
    "profile": [
      "http://hl7.org/fhir/StructureDefinition/shareablecodesystem"
    ]
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "oo"
    }
  ],
  "url": "http://terminology.hl7.org/CodeSystem/referencerange-meaning",
  "identifier": [
    {
      "system": "urn:ietf:rfc:3986",
      "value": "urn:oid:2.16.840.1.113883.4.642.1.1124"
    }
  ],
  "version": "4.0.0",
  "name": "ObservationReferenceRangeMeaningCodes",
  "title": "Observation Reference Range Meaning Codes",
  "status": "draft",
  "experimental": false,
  "publisher": "FHIR Project team",
  "contact": [
    {
      "telecom": [
        {
          "system": "url",
          "value": "http://hl7.org/fhir"
        }
      ]
    }
  ],
  "description": "This value set defines a set of codes that can be used to indicate the meaning/use of a reference range for a particular target population.",
  "caseSensitive": true,
  "valueSet": "http://hl7.org/fhir/ValueSet/referencerange-meaning",
  "hierarchyMeaning": "is-a",
  "content": "complete",
  "property": [
    {
      "code": "abstract",
      "description": "True if an element is considered 'abstract' - in otherwords, the code is not for use as a real concept",
      "type": "boolean"
    }
  ],
  "concept": [
    {
      "code": "type",
      "display": "Type",
      "definition": "General types of reference range.",
      "property": [
        {
          "code": "abstract",
          "valueBoolean": true
        }
      ],
      "concept": [
        {
          "code": "normal",
          "display": "Normal Range",
          "definition": "Values expected for a normal member of the relevant control population being measured. Typically each results producer such as a laboratory has specific normal ranges and they are usually defined as within two standard deviations from the mean and account for 95.45% of this population."
        },
        {
          "code": "recommended",
          "display": "Recommended Range",
          "definition": "The range that is recommended by a relevant professional body."
        },
        {
          "code": "treatment",
          "display": "Treatment Range",
          "definition": "The range at which treatment would/should be considered."
        },
        {
          "code": "therapeutic",
          "display": "Therapeutic Desired Level",
          "definition": "The optimal range for best therapeutic outcomes.",
          "concept": [
            {
              "code": "pre",
              "display": "Pre Therapeutic Desired Level",
              "definition": "The optimal range for best therapeutic outcomes for a specimen taken immediately before administration."
            },
            {
              "code": "post",
              "display": "Post Therapeutic Desired Level",
              "definition": "The optimal range for best therapeutic outcomes for a specimen taken immediately after administration."
            }
          ]
        }
      ]
    },
    {
      "code": "endocrine",
      "display": "Endocrine",
      "definition": "Endocrine related states that change the expected value.",
      "property": [
        {
          "code": "abstract",
          "valueBoolean": true
        }
      ],
      "concept": [
        {
          "code": "pre-puberty",
          "display": "Pre-Puberty",
          "definition": "An expected range in an individual prior to puberty."
        },
        {
          "code": "follicular",
          "display": "Follicular Stage",
          "definition": "An expected range in an individual during the follicular stage of the cycle."
        },
        {
          "code": "midcycle",
          "display": "MidCycle",
          "definition": "An expected range in an individual during the midcycle stage of the cycle."
        },
        {
          "code": "luteal",
          "display": "Luteal",
          "definition": "An expected range in an individual during the luteal stage of the cycle."
        },
        {
          "code": "postmenopausal",
          "display": "Post-Menopause",
          "definition": "An expected range in an individual post-menopause."
        }
      ]
    }
  ]
}