{
  "resourceType": "Bundle",
  "id": "report",
  "type": "collection",
  "entry": [
    {
      "fullUrl": "https://example.com/base/DiagnosticReport/report",
      "resource": {
        "resourceType": "DiagnosticReport",
        "id": "report",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: report</p><p><b>status</b>: final</p><p><b>code</b>: comprehensive bone marrow report <span>(Details )</span></p><p><b>subject</b>: <a>Everywoman, Eve A, MRN: 123456789</a></p><p><b>effective</b>: 02/01/2015 1:20:10 PM</p><p><b>issued</b>: 06/01/2015 1:20:10 PM</p><p><b>performer</b>: <a>Molecular Diagnostic Laboratory</a></p><p><b>specimen</b>: <a>Bone marrow ID: MLD45-Z4-1234</a></p><p><b>result</b>: </p><ul><li><a>Observation/o1</a></li><li><a>Observation/o2</a></li><li><a>Observation/o3</a></li><li><a>Observation/o4</a></li><li><a>Observation/o5</a></li><li><a>Observation/o6</a></li><li><a>Observation/o7</a></li><li><a>Observation/o8</a></li><li><a>Observation/o9</a></li><li><a>Observation/o10</a></li><li><a>Observation/o11</a></li><li><a>Observation/o12</a></li><li><a>Observation/o13</a></li></ul></div>"
        },
        "extension": [
          {
            "url": "http://hl7.org/fhir/StructureDefinition/DiagnosticReport-geneticsAssessedCondition",
            "valueReference": {
              "reference": "Condition/c1"
            }
          }
        ],
        "status": "final",
        "code": {
          "text": "comprehensive bone marrow report"
        },
        "subject": {
          "reference": "Patient/genetics-example1",
          "display": "Everywoman, Eve A, MRN: 123456789"
        },
        "effectiveDateTime": "2015-01-02T13:20:10+01:00",
        "issued": "2015-01-06T13:20:10+01:00",
        "performer": [
          {
            "reference": "Practitioner/genetics-example1",
            "display": "Molecular Diagnostic Laboratory"
          }
        ],
        "specimen": [
          {
            "reference": "Specimen/genetics-example1",
            "display": "Bone marrow ID: MLD45-Z4-1234"
          }
        ],
        "result": [
          {
            "reference": "Observation/o1"
          },
          {
            "reference": "Observation/o2"
          },
          {
            "reference": "Observation/o3"
          },
          {
            "reference": "Observation/o4"
          },
          {
            "reference": "Observation/o5"
          },
          {
            "reference": "Observation/o6"
          },
          {
            "reference": "Observation/o7"
          },
          {
            "reference": "Observation/o8"
          },
          {
            "reference": "Observation/o9"
          },
          {
            "reference": "Observation/o10"
          },
          {
            "reference": "Observation/o11"
          },
          {
            "reference": "Observation/o12"
          },
          {
            "reference": "Observation/o13"
          }
        ]
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o1",
      "resource": {
        "resourceType": "Observation",
        "id": "o1",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o1</p><p><b>status</b>: final</p><p><b>code</b>: Leukocytes [#/volume] in Blood <span>(Details : {LOINC code '26464-8' = 'Leukocytes [#/volume] in Blood', given as 'Leukocytes [#/volume] in Blood'})</span></p><p><b>value</b>: 31.9 K/ul</p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "26464-8",
              "display": "Leukocytes [#/volume] in Blood"
            }
          ]
        },
        "valueQuantity": {
          "value": 31.9,
          "unit": "K/ul"
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o2",
      "resource": {
        "resourceType": "Observation",
        "id": "o2",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o2</p><p><b>status</b>: final</p><p><b>code</b>: Hematocrit [Volume Fraction] of Blood <span>(Details : {LOINC code '20570-8' = 'Hematocrit [Volume Fraction] of Blood', given as 'Hematocrit [Volume Fraction] of Blood'})</span></p><p><b>value</b>: 27 %</p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "20570-8",
              "display": "Hematocrit [Volume Fraction] of Blood"
            }
          ]
        },
        "valueQuantity": {
          "value": 27,
          "unit": "%"
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o3",
      "resource": {
        "resourceType": "Observation",
        "id": "o3",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o3</p><p><b>status</b>: final</p><p><b>code</b>: Platelets [#/volume] in Blood <span>(Details : {LOINC code '26515-7' = 'Platelets [#/volume] in Blood', given as 'Platelets [#/volume] in Blood'})</span></p><p><b>value</b>: 84 K/ul</p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "26515-7",
              "display": "Platelets [#/volume] in Blood"
            }
          ]
        },
        "valueQuantity": {
          "value": 84,
          "unit": "K/ul"
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o4",
      "resource": {
        "resourceType": "Observation",
        "id": "o4",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o4</p><p><b>status</b>: final</p><p><b>code</b>: NPM1 gene mutations found [Identifier] in Bone marrow by Molecular genetics method Nominal <span>(Details : {LOINC code '75034-9' = 'NPM1 gene mutations found [Identifier] in Bone marrow by Molecular genetics method Nominal', given as 'NPM1 gene mutations found [Identifier] in Bone marrow by Molecular genetics method Nominal'})</span></p><p><b>value</b>: Positive <span>(Details : {SNOMED CT code '10828004' = 'Positive', given as 'Positive'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "75034-9",
              "display": "NPM1 gene mutations found [Identifier] in Bone marrow by Molecular genetics method Nominal"
            }
          ]
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "10828004",
              "display": "Positive"
            }
          ]
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o5",
      "resource": {
        "resourceType": "Observation",
        "id": "o5",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o5</p><p><b>status</b>: final</p><p><b>code</b>: FLT3 gene mutation analysis in Bone marrow by Molecular genetics method Narrative <span>(Details : {LOINC code '54447-8' = 'FLT3 gene mutation analysis in Bone marrow by Molecular genetics method Narrative', given as 'FLT3 gene mutation analysis in Bone marrow by Molecular genetics method Narrative'})</span></p><p><b>value</b>: Negative <span>(Details : {SNOMED CT code '260385009' = 'Negative', given as 'Negative'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "54447-8",
              "display": "FLT3 gene mutation analysis in Bone marrow by Molecular genetics method Narrative"
            }
          ]
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "260385009",
              "display": "Negative"
            }
          ]
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o6",
      "resource": {
        "resourceType": "Observation",
        "id": "o6",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o6</p><p><b>status</b>: final</p><p><b>code</b>: KIT gene mutation analysis in Bone marrow by Molecular genetics method Narrative <span>(Details : {LOINC code '55201-8' = 'KIT gene mutation analysis in Blood or Tissue by Molecular genetics method Narrative', given as 'KIT gene mutation analysis in Bone marrow by Molecular genetics method Narrative'})</span></p><p><b>value</b>: Negative <span>(Details : {SNOMED CT code '260385009' = 'Negative', given as 'Negative'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "55201-8",
              "display": "KIT gene mutation analysis in Bone marrow by Molecular genetics method Narrative"
            }
          ]
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "260385009",
              "display": "Negative"
            }
          ]
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o7",
      "resource": {
        "resourceType": "Observation",
        "id": "o7",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o7</p><p><b>status</b>: final</p><p><b>code</b>: Myeloblasts [#/volume] in Blood <span>(Details : {LOINC code '30444-4' = 'Myeloblasts [#/volume] in Blood', given as 'Myeloblasts [#/volume] in Blood'})</span></p><p><b>value</b>: Positive <span>(Details : {SNOMED CT code '10828004' = 'Positive', given as 'Positive'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "30444-4",
              "display": "Myeloblasts [#/volume] in Blood"
            }
          ]
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "10828004",
              "display": "Positive"
            }
          ]
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o8",
      "resource": {
        "resourceType": "Observation",
        "id": "o8",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o8</p><p><b>status</b>: final</p><p><b>code</b>: CD4 Ag [Presence] in Tissue by Immune stain <span>(Details : {LOINC code '47016-1' = 'CD4 Ag [Presence] in Tissue by Immune stain', given as 'CD4 Ag [Presence] in Tissue by Immune stain'})</span></p><p><b>value</b>: Positive <span>(Details : {SNOMED CT code '10828004' = 'Positive', given as 'Positive'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "47016-1",
              "display": "CD4 Ag [Presence] in Tissue by Immune stain"
            }
          ]
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "10828004",
              "display": "Positive"
            }
          ]
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o9",
      "resource": {
        "resourceType": "Observation",
        "id": "o9",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o9</p><p><b>status</b>: final</p><p><b>code</b>: CD13 Ag [Presence] in Tissue by Immune stain <span>(Details : {LOINC code '49464-1' = 'CD13 Ag [Presence] in Tissue by Immune stain', given as 'CD13 Ag [Presence] in Tissue by Immune stain'})</span></p><p><b>value</b>: Positive <span>(Details : {SNOMED CT code '10828004' = 'Positive', given as 'Positive'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "49464-1",
              "display": "CD13 Ag [Presence] in Tissue by Immune stain"
            }
          ]
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "10828004",
              "display": "Positive"
            }
          ]
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o10",
      "resource": {
        "resourceType": "Observation",
        "id": "o10",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o10</p><p><b>status</b>: final</p><p><b>code</b>: CD2 Ag [Presence] in Tissue by Immune stain <span>(Details : {LOINC code '49466-6' = 'CD2 Ag [Presence] in Tissue by Immune stain', given as 'CD2 Ag [Presence] in Tissue by Immune stain'})</span></p><p><b>value</b>: Negative <span>(Details : {SNOMED CT code '260385009' = 'Negative', given as 'Negative'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "49466-6",
              "display": "CD2 Ag [Presence] in Tissue by Immune stain"
            }
          ]
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "260385009",
              "display": "Negative"
            }
          ]
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o11",
      "resource": {
        "resourceType": "Observation",
        "id": "o11",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o11</p><p><b>status</b>: final</p><p><b>code</b>: Karyotype [Identifier] in Bone marrow Nominal <span>(Details : {LOINC code '33893-9' = 'Karyotype [Identifier] in Bone marrow Nominal', given as 'Karyotype [Identifier] in Bone marrow Nominal'})</span></p><p><b>value</b>: 46,XX[20] <span>(Details )</span></p></div>"
        },
        "status": "final",
        "code": {
          "coding": [
            {
              "system": "http://loinc.org",
              "code": "33893-9",
              "display": "Karyotype [Identifier] in Bone marrow Nominal"
            }
          ]
        },
        "valueCodeableConcept": {
          "text": "46,XX[20]"
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o12",
      "resource": {
        "resourceType": "Observation",
        "id": "o12",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o12</p><p><b>status</b>: final</p><p><b>code</b>: MDS-associated genetic abnormalities <span>(Details )</span></p><p><b>value</b>: Negative <span>(Details : {SNOMED CT code '260385009' = 'Negative', given as 'Negative'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "text": "MDS-associated genetic abnormalities"
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "260385009",
              "display": "Negative"
            }
          ]
        }
      }
    },
    {
      "fullUrl": "https://example.com/base/Observation/o13",
      "resource": {
        "resourceType": "Observation",
        "id": "o13",
        "text": {
          "status": "generated",
          "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: o13</p><p><b>status</b>: final</p><p><b>code</b>: AML-associated genetic abnormalities <span>(Details )</span></p><p><b>value</b>: Negative <span>(Details : {SNOMED CT code '260385009' = 'Negative', given as 'Negative'})</span></p></div>"
        },
        "status": "final",
        "code": {
          "text": "AML-associated genetic abnormalities"
        },
        "valueCodeableConcept": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "260385009",
              "display": "Negative"
            }
          ]
        }
      }
    }
  ],
  "meta": {
    "tag": [
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ActReason",
        "code": "HTEST",
        "display": "test health data"
      }
    ]
  }
}