Straightforward:

*`Hello, World!

Less obvious way:

>`ld!
`
 r
  o
   W
    `
     b` ,olleH`_

Even less obvious, demonstrating the creation and execution order of instruction pointers, and the hexagonal layout of beeswax programs:

r  l
 l o
  ``
ol`*`,d!
   ``
   e H
   W