hmmsearch - search a sequence database with a profile HMM
HMMER 2.2g (August 2001)
Copyright (C) 1992-2001 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file:                   /sw/share/hmmer/demo/7tm_1 [7tm_1]
Sequence database:          /sw/share/hmmer/demo/P08908.fasta
per-sequence score cutoff:  [none]
per-domain score cutoff:    [none]
per-sequence Eval cutoff:   <= 10        
per-domain Eval cutoff:     [none]
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Query HMM:   7tm_1
Accession:   PF00001
Description: 7 transmembrane receptor (rhodopsin family)
  [HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence             Description                        Score    E-value  N 
--------             -----------                        -----    ------- ---
sp|P08908|5H1A_HUMAN 5-hydroxytryptamine 1A receptor    377.1   5.5e-130   1

Parsed for domains:
Sequence             Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------             ------- ----- -----    ----- -----      -----  -------
sp|P08908|5H1A_HUMAN   1/1      53   400 ..     1   275 []   377.1 5.5e-130

Alignments of top-scoring domains:
sp|P08908|5H1A_HUMAN: domain 1 of 1, from 53 to 400: score 377.1, E = 5.5e-130
                   *->GNlLVilvilrtkklrtptnifilNLAvADLLflltlppwalyylvg
                      GN+ V+++i+++++l++++n++i++LAv+DL+++++++p+a++y v 
  sp|P08908|    53    GNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVL 99   

                   gsedWpfGsalCklvtaldvvnmyaSillLtaISiDRYlAIvhPlryrrr
                   +   W++G++ C+l++aldv+++++Sil+L+aI++DRY+AI++P+ y ++
  sp|P08908|   100 N--KWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNK 147  

                   rtsprrAkvvillvWvlalllslPpllfswvktveegngtlnvnvtvCli
                   rt prrA+++i+l+W++++l+s+Pp +++w++++  +         +C+i
  sp|P08908|   148 RT-PRRAAALISLTWLIGFLISIPP-MLGWRTPEDRSD------PDACTI 189  

                   dfpeestasvstwlvsyvllstlvgFllPllvilvcYtrIlrtlrkrark
                   + +++           y+++st+++F++Pll++lv+Y+rI+r++r r rk
  sp|P08908|   190 SKDHG-----------YTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK 228  

                   gas...............................................
                    + + ++++ +++++ ++ ++++++ ++++++++ + + +++ ++    +
  sp|P08908|   229 TVKkvektgadtrhgaspapqpkksvngesgsrnwrlgveskaggalcan 278  

                   ..................................................
                   +  ++++++   +  + ++ ++++++ + +++ ++++  + + +++++++
  sp|P08908|   279 gavrqgddgaalevievhrvgnskehlplpseagptpcapasferknern 328  

                   .....kkrsskerkaaktllvvvvvFvlCWlPyfivllldtlc.lsiims
                    + ++k+   +erk++ktl++++++F+lCWlP+fiv+l+ ++c++s++m 
  sp|P08908|   329 aeakrKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCeSSCHM- 377  

                   stCelervlptallvtlwLayvNsclNPiIY<-*
                           +  +  +++wL+y+Ns lNP+IY   
  sp|P08908|   378 --------PTLLGAIINWLGYSNSLLNPVIY    400  


Histogram of all scores:
score    obs    exp  (one = represents 1 sequences)
-----    ---    ---
  377      1      0|=                                                          


% Statistical details of theoretical EVD fit:
              mu =   -10.6639
          lambda =     0.7676
chi-sq statistic =     0.0000
  P(chi-square)  =          0

Total sequences searched: 1

Whole sequence top hits:
tophits_s report:
     Total hits:           1
     Satisfying E cutoff:  1
     Total memory:         16K

Domain top hits:
tophits_s report:
     Total hits:           1
     Satisfying E cutoff:  1
     Total memory:         17K